The studies below concern ingredients in Lysa.
The sources are primarily peer-reviewed; some entries are protocols/registries or review articles.
Below is a selection of documented and published studies on niacinamide in skincare.
Randomized split-face, 4% niacinamide, 8 weeks → Fewer wrinkles in the eye area vs. control.
DB, vehicle-controlled, 10 weeks; niacinamide + N-acetylglucosamine → Less uneven pigmentation than vehicle.
Clinical cream study (JAAD) → Improved texture, reduced hyperpigmentation and redness.
Link
RCT, oral nicotinamide, 12 months → Lower TEWL (better barrier) over time vs. placebo.
RCT, 5% niacinamide moisturizer → Lightens dark spots and improves barrier markers.
Randomized split-face, 4% niacinamide → Anti-wrinkle effect confirmed.
Clinical serum study → Improved barrier/hydration and skin tone.
RCT, drink with niacinamide + tomato extract → Improvements in skin parameters (parallel-controlled).
Acne pilot, 4% niacinamide gel, 8 weeks → Significant reduction in lesions.
Review (acne) → 6/8 topical niacinamide studies show significant improvement.
Overview of clinical and controlled studies on salicylic acid in skincare.
DB, placebo-controlled; 2% SA cleanser → Clear reduction in mild/moderate acne.
Link